TECHNE is a practice-based research initiative in the digitally-expanded intermedia arts and writing founded in 2000 by Professor Mark Amerika at the University of Colorado at Boulder. TECHNE develops innovative research methodologies that lead to the invention of new forms of intermedia art, writing, performance, and scholarly research. Recent research outcomes include digital art and humanities projects distributed over the Internet, live audio/visual performances, transmedia narratives, hybdrized print and electronic publications, interactive museum installations, mobile cinema and art applications for personal phones and tablets.

In 2002, Founding Faculty Director Mark Amerika wrote the TECHNE white paper, one of the first attempts at an American university to introduce a practice-based research platform for artists working in the post-Internet era. The paper was modeled after two seemingly disparate sources: computer scientist Douglas Englebart's white paper on Augmenting Human Intellect: A Conceptual Framework written 40 years before the TECHNE paper, and Amerika's own "Avant-Pop Manifesto"that helped launch a conceptual space for new forms of writing and art in the Internet era. The paper can be read in full here.

The TECHNE website includes links to faculty and graduate student research projects and archives the original "Histories of Internet Art: Fictions and Factions" exhibition curated, designed, and implemented by digital art undegraduates during the years 2002-2009.